Preoperative Extracorporeal Irradiation of the Blood as Adjunctive Immunosuppression in Human Renal Transplantation
نویسندگان
چکیده
منابع مشابه
Role of Immunosuppression Minimization Protocols in Renal Transplantation
The subject of transplant immunosuppression has generated significant interest in recent years. Excellent immunosuppression, advances in surgical technique, post-transplantation care, and infection control have resulted in excellent outcomes. There is widespread support for the notion that the fundamental objective in transplant immunology should be the achievement of specific graft toleran...
متن کاملIMMUNOSUPPRESSION BEFORE CYCLOSPORINE Renal Transplantation
The concept of liver transplantation is a relatively recent one. The first descriptions of liver replacement in experimental animals were published less than 25 years ago,I,2 and the first attempt at clinical liver transplantation was not made until March I, 1963.3 The pace of clinical trials remained limited until 1980, the year when the new immunosuppressive agent cyclosporine was introduced....
متن کاملOverview of Immunosuppression in Renal Transplantation
Half life appears to be the best way to give the patient a general understanding of how long their transplant may last. The graft half life for deceased donor transplants has increased from 6.6 years in 1989 to 8.8 years by 2005. Significant progress has also been made in high risk transplants where graft half life has improved from 3 years in 1989 to 6.4 years in 2005 for expanded criteria don...
متن کاملExtracorporeal Irradiation of Blood (ECIB) in Man
LL PRESENT FORMS OF THERAPY for acute myelocytic leukemia (AML) injure or destroy normal as well as leukemic cells. The action of anti-metabolic chemotherapeutic drugs is largely directed at disrupting flucleic acid synthesis and, thus, replication of cells. The alkylating agents and whole body radiation are effective in reducing cell production by slowing the generative cycle and directly kill...
متن کاملSteps in immunosuppression for renal transplantation.
The technical feasibility of renal transplantation was established from the identical-twin experience in the 1950's [1]. The way in which these transplantations in the absence of an immunologic barrier contributed to the long and complex history of this field has been described in other reviews [2. 31. The next and more difficult task was to develop techniques to prevent the rejection that foll...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1971
ISSN: 0003-4932
DOI: 10.1097/00000658-197111000-00011